CLINICAL TRIALS
AND STUDIES CONDUCTED AT KAVI
The first HIV vaccine clinical trial began in February 2001
and to date five HIV vaccine clinical trials have been conducted
and completed at KAVI. Four phase-I trials and one phase-II
trial.
|
1. Vaccine Trials
conducted at KAVI-KNH
| Protocol |
Description |
Date
of enrollment |
No.
of volunteers |
Status |
| IAVI-002 |
Phase 1 Clinical Trial |
2001 |
18
|
Completed |
| IAVI-004 |
Phase 1 Clinical Trial |
2002 |
18
|
Completed |
| IAVI-008 |
Phase 1 Clinical Trial |
2003 |
10
|
Completed |
| IAVI-010 |
Phase 2A Clinical Trial |
2003 |
70
|
Completed |
| V001 |
Phase 1 Clinical Trial |
2005 |
57 |
Completed |
2. Studies conducted at KAVI-KNH
| Protocol |
Description |
Date
of enrollment |
No.
of volunteers |
Status |
| IAVI-D |
Laboratory Reference Ranges |
2004 |
200
|
Completed |
| IAVI-G |
Cross-sectional |
2007 |
200
|
Completed |
| IAVI-LTFU |
Longitudinal |
2007 |
114
|
Ongoing |
| IAVI-J |
Mucosal Sampling |
2010 |
15
|
Ongoing |
|
| |
|
| 3. Studies conducted
at KAVI-Kangemi |
|
|
| Protocol |
Description |
Date
of enrollment |
No.
of volunteers |
Status |
| IAVI-A |
HIV prevalence |
6th April 2004 |
1000
|
Completed |
| IAVI-D |
Laboratory Reference Ranges |
18th April 2005 |
400
|
Completed |
| IAVI-Closed B |
HIV incidence |
9th January 2006 |
700
|
Completed |
| IAVI-C |
New infections |
15th March 2006 |
23
|
Ongoing |
| IAVI-Open B |
HIV incidence |
7th April 2008 |
500 |
Ongoing |
| IAVI-PrEP |
Pre-Exposure Prophylaxis (PrEP) |
October 2009 |
36 |
Completed |
|
|
